Handbook Of Innovations In Central Nervous System Regenerative Medicine

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Handbook of Innovations in Central Nervous System Regenerative Medicine

Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. - Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance - Discusses the limitations of present therapies used in the clinics - Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies - Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path
Oxford Textbook of Neurocritical Care

Author: Martin Smith
language: en
Publisher: Oxford University Press
Release Date: 2025-05-14
Neurocritical care is a multidisciplinary specialty that provides comprehensive management for all life-threatening disorders of the central nervous system and their complications. Increased understanding of the pathophysiology of acute central nervous system disorders and their impact on systemic organ systems, in association with advances in neuromonitoring and neuroimaging techniques, has led to the introduction of more effective and individualised treatment strategies that have translated into improved outcomes for critically ill neurological patients. As well as treatments targeted to the acute neurological disorder, critically ill neurological patients require meticulous general intensive care support to maintain systemic physiological stability and optimize neurological outcomes. The second edition of the Oxford Textbook of Neurocritical Care brings together international experts from various disciplines to provide a comprehensive global perspective on this field. In 33 updated or new chapters, the book discusses the pathophysiology of acute neurological conditions, advancements in monitoring and imaging techniques, evidenced-based treatment strategies, prognostication, patient outcomes, and ethics. Each chapter highlights advancements within specific areas and underscores the critical attention to detail that is the basis of neurocritical care practice. While primarily designed for those in the neurocritical care field, this textbook also serves as a valuable resource for other clinical professionals who encounter patients with acute neurological conditions in their practice. It is also a useful resource for trainees from many disciplines
Nanomedical Drug Delivery for Neurodegenerative Diseases

Nanomedical Drug Delivery for Neurodegenerative Diseases opens the door for promising approaches and advances in the diagnosis and treatment of various neurodegenerative diseases. The contents of the book comprise all the aspects related to the design, synthesis, and application of different nanodrug delivery systems in the treatment of neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases. This book explores how nanoparticulate drug carriers can improve therapeutic efficacy by selecting a suitable design strategy. Nanomedical Drug Delivery for Neurodegenerative Diseases is a valuable resource for graduates, clinical researchers, and other scientists working to minimize the challenges to deliver the drugs and genes in a more efficient and targeted manner for the treatment of neurodegenerative diseases. - Includes design, synthesis and applications of drug delivery systems - Explores the role of nanotechnology in the diagnosis and treatment of neurodegenerative disorders - Reviews applications for the management of Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases - Discusses extracellular vesicles and mitochondria-targeted bioactive delivery systems - Details how nanocarrier-based delivery is useful to improve efficacy and cure