General Anesthesia From Theory To Experiments
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General Anesthesia: From Theory to Experiments
General anesthesia is a standard medical procedure in today's hospital practice. Although in most cases the administration of anesthetics does not affect severely the patients health, side effects of anesthesia are well-known, such as nausea or cognitive impairment. Moreover 1-2 out of 1000 patients under surgery report a partial wake up from anesthesia during the operation. The reason for such a partial lack of control of depth of anesthesia is that medical procedures are highly optimized based on experience but the neural dynamics during general anesthesia is far from being understood. One reason for this lack of understanding is both the complex neural interactions of neurons on different spatial and temporal scales and the poorly understood action of anesthetics on neural populations. For instance, anesthetic agents act on synaptic receptors on a microscopic scale essentially evoking a macroscopic change of population activity, such as Local Field Potentials, EEG/MEG or resulting change of cerebral blood flow. This population effect then triggers the loss of consciousness in patients. This Research Topic aims to address recent theoretical and experimental advances in the field. The theoretical and experimental studies represent a good overview over the current state of research in the field and provides a deeper insight into the underlying neural mechanisms. Each article in the issue focusses on a specific current research topic in general anesthesia research and several articles introduce to the topic in a pedagogical way. The issue covers various types of anaesthesia and the most important topics in the field, such as (but not limited to) recent advances in theoretical models and states of consciousness reflected in experimental data, the connectivity changes observed during anesthesia or effects of specific drugs on brain activity. The introduction style of the papers facilitates the reader to understand the background of the research aspect and even allows readers not familiar with general anesthesia research to enter the research domain. Hence the Research Topic aims to provide on one hand an overview of the current state of the art and on the other hand a good starting point for new researchers in the field.
General Anesthesia: From Theory to Experiments
General anesthesia is a standard medical procedure in today's hospital practice. Although in most cases the administration of anesthetics does not affect severely the patients health, side effects of anesthesia are well-known, such as nausea or cognitive impairment. Moreover 1-2 out of 1000 patients under surgery report a partial wake up from anesthesia during the operation. The reason for such a partial lack of control of depth of anesthesia is that medical procedures are highly optimized based on experience but the neural dynamics during general anesthesia is far from being understood. One reason for this lack of understanding is both the complex neural interactions of neurons on different spatial and temporal scales and the poorly understood action of anesthetics on neural populations. For instance, anesthetic agents act on synaptic receptors on a microscopic scale essentially evoking a macroscopic change of population activity, such as Local Field Potentials, EEG/MEG or resulting change of cerebral blood flow. This population effect then triggers the loss of consciousness in patients. This Research Topic aims to address recent theoretical and experimental advances in the field. The theoretical and experimental studies represent a good overview over the current state of research in the field and provides a deeper insight into the underlying neural mechanisms. Each article in the issue focusses on a specific current research topic in general anesthesia research and several articles introduce to the topic in a pedagogical way. The issue covers various types of anaesthesia and the most important topics in the field, such as (but not limited to) recent advances in theoretical models and states of consciousness reflected in experimental data, the connectivity changes observed during anesthesia or effects of specific drugs on brain activity. The introduction style of the papers facilitates the reader to understand the background of the research aspect and even allows readers not familiar with general anesthesia research to enter the research domain. Hence the Research Topic aims to provide on one hand an overview of the current state of the art and on the other hand a good starting point for new researchers in the field.
Nurse Anesthesia - E-Book
Author: Sass Elisha
language: en
Publisher: Elsevier Health Sciences
Release Date: 2013-02-08
Take your understanding to a whole new level with Pageburst digital books on VitalSource! Easy-to-use, interactive features let you make highlights, share notes, run instant topic searches, and so much more. Best of all, with Pageburst, you get flexible online, offline, and mobile access to all your digital books. Written specifically for nurse anesthetists, Nurse Anesthesia, 5th Edition provides comprehensive coverage of both scientific principles and evidence-based practice. It offers a complete overview of anatomy, physiology, pharmacology, and pathophysiology, and offers practical coverage of equipment and anesthesia management. This edition includes updated information on pharmacokinetics, clinical monitoring, drug delivery systems, and complications, and revises chapters on airway management and anesthesia for cardiac surgery. Written by leading nurse anesthesia experts John Nagelhout and Karen Plaus, this perennial bestseller prepares anesthesia students and CRNAs for today's clinical anesthesia practice. Over 650 figures of anatomy, nurse anesthesia procedures, and equipment depict complex concepts and information. An easy-to-use organization covers basic principles first, and builds on those with individual chapters for each surgical specialty. UPDATED references make it quick and simple to find the latest and most important research in the field. Over 700 tables and boxes highlight the most essential information in a quick, easy-to-reference format. Expert CRNA authors provide the current clinical information you’ll use in daily practice. UPDATED pharmacology information includes pharmacokinetics, drug delivery systems, opiate antagonists, and key induction drugs. Over 100 NEW photos and illustrations enhance your understanding of difficult anesthesia concepts. UPDATED Airway Management and Anesthesia for Cardiac Surgery chapters are thoroughly revised. NEW coverage includes robotics, screening applications, and non-operating room best practices.