Functionalized Magnetic Nanoparticles For Theranostic Applications
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Functionalized Magnetic Nanoparticles for Theranostic Applications
This unique book provides a comprehensive introduction to the multifaceted realm of functionalized magnetic nanoparticles in the field of theranostics, exploring the fundamental concepts, synthesis methods, characterization techniques, and potential applications. In recent years, the intersection of nanotechnology and medicine has ushered in a new era of therapeutics and diagnostics. Among the myriad nanostructures, magnetic nanoparticles (MNPs) have emerged as versatile candidates with immense potential for theranostic applications. Their unique combination of magnetic properties and functionalization capabilities has paved the way for innovative approaches in both the diagnosis and treatment of various diseases. Understanding the synthesis, characterization, and manipulation of these MNPs is essential for harnessing their full potential in theranostics. Advances in nanotechnology have enabled precise control over their size, shape, and surface chemistry, allowing for tailored functionalities to suit specific biomedical applications. From superparamagnetic iron oxide nanoparticles (SPIONs) to magnetic nanorods and beyond, the diverse landscape of MNPs offers a rich playground for innovation. The convergence of diagnosis and therapy is facilitated by functionalized MNPs; their magnetic properties render them invaluable tools for imaging modalities such as magnetic resonance imaging (MRI), offering high-resolution anatomical and functional information for disease detection and monitoring. Simultaneously, functionalizing MNPs with targeting ligands, therapeutic agents, or stimuli-responsive moieties empowers them to actively engage in targeted drug delivery, hyperthermia, or magnetic manipulation of biological processes. This synergistic approach exemplifies the essence of theranostics—combining therapy and diagnostics to achieve personalized and precise medical interventions. The book discusses the challenges ahead, including the translation of functionalized MNPs from bench to bedside, which necessitates rigorous preclinical and clinical evaluations to ensure safety, efficacy, and biocompatibility. Moreover, the complex interplay between nanoparticles and biological systems demands a multidisciplinary approach, bridging the gap between materials science, biology, and clinical medicine. Regulatory hurdles, scalability issues, and ethical considerations further underscore the need for concerted efforts and strategic collaborations in the development and commercialization of MNP-based theranostic platforms. The readers will find that “Functionalized Magnetic Nanoparticles for Theranostic Applications” comprehensively covers the chemical, structural, and biological properties of functionalized magnetic nanoparticles for theranostic applications as well as most of the challenges. Audience This unique reference book will be of great value to materials engineers, polymer scientists, and technologists working in the electronic, electrical, and biomedical industries. It will also be of great use to graduate, postgraduate, and engineering students working in materials and polymer science.
Magnetic Nanoparticles in Human Health and Medicine
Magnetic Nanoparticles in Human Health and Medicine Explores the application of magnetic nanoparticles in drug delivery, magnetic resonance imaging, and alternative cancer therapy Magnetic Nanoparticles in Human Health and Medicine addresses recent progress in improving diagnosis by magnetic resonance imaging (MRI) and using non-invasive and non-toxic magnetic nanoparticles for targeted drug delivery and magnetic hyperthermia. Focusing on cancer diagnosis and alternative therapy, the book covers both fundamental principles and advanced theoretical and experimental research on the magnetic properties, biocompatibilization, biofunctionalization, and application of magnetic nanoparticles in nanobiotechnology and nanomedicine. Chapters written by a panel of international specialists in the field of magnetic nanoparticles and their applications in biomedicine cover magnetic hyperthermia (MHT), MRI contrast agents, biomedical imaging, modeling and simulation, nanobiotechnology, toxicity issues, and more. Readers are provided with accurate information on the use of magnetic nanoparticles in diagnosis, drug delivery, and alternative cancer therapeutics—featuring discussion of current problems, proposed solutions, and future research directions. Topics include current applications of magnetic iron oxide nanoparticles in nanomedicine and alternative cancer therapy: drug delivery, magnetic resonance imaging, superparamagnetic hyperthermia as alternative cancer therapy, magnetic hyperthermia in clinical trials, and simulating the physics of magnetic particle heating for cancer therapy. This comprehensive volume: Covers both general research on magnetic nanoparticles in medicine and specific applications in cancer therapeutics Discusses the use of magnetic nanoparticles in alternative cancer therapy by magnetic and superparamagnetic hyperthermia Explores targeted medication delivery using magnetic nanoparticles as a future replacement of conventional techniques Reviews the use of MRI with magnetic nanoparticles to increase the diagnostic accuracy of medical imaging Magnetic Nanoparticles in Human Health and Medicine is a valuable resource for researchers in the fields of nanomagnetism, magnetic nanoparticles, nanobiomaterials, nanobioengineering, biopharmaceuticals nanobiotechnologies, nanomedicine, and biopharmaceuticals, particularly those focused on alternative cancer diagnosis and therapeutics.
Analytical Applications of Functionalized Magnetic Nanoparticles
Author: Chaudhery Mustansar Hussain
language: en
Publisher: Royal Society of Chemistry
Release Date: 2021-07-27
Magnetic nanoparticles (MNPs) uniquely combine superparamagnetic performance with dimensions that are smaller than or similar size to molecular analytes. Recently, functionalized MNPs are predicted to be a driver for technology and business in this century and hold the promise of high performance materials that will significantly influence all aspects of society. Functionalized MNPs are creating new possibilities for development and innovation in different analytical procedures. Despite their participation in modern development, they are in their infancy and largely unexplored for their practical applications in analysis. This book will provide quality research and practical guidance to analytical scientists, researchers, engineers, quality control experts and laboratory specialists. It covers applications of functionalized MNPs in all stages of analytical procedures. Their incorporation has opened new possibilities for sensing, extraction and detection enabling an increase in sensitivity, magnifying precision and improvement in the detection limit of modern analysis. Toxicity, safety, risk, and legal aspects of functionalized MNPs and the future of analytical chemistry with respect to their use is covered. The book provides an integrated approach for advanced analytical methods and techniques for postgraduates and researchers looking for a reference outlining new and advanced techniques surrounding the applications of functionalized nanomaterials in analytical chemistry.