Folding For The Synapse


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Folding for the Synapse


Folding for the Synapse

Author: Andreas Wyttenbach

language: en

Publisher: Springer Science & Business Media

Release Date: 2010-10-22


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Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex. This book will introduce both important concepts of folding machineries and give examples of the biological relevance of further chaperone functions.

Folding for the Synapse


Folding for the Synapse

Author: Andreas Wyttenbach

language: en

Publisher: Springer

Release Date: 2011-07-21


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Folding for the Synapse addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex. This book will introduce both important concepts of folding machineries and give examples of the biological relevance of further chaperone functions.

Structural and Functional Organization of the Synapse


Structural and Functional Organization of the Synapse

Author: Johannes W. Hell

language: en

Publisher: Springer Science & Business Media

Release Date: 2008-06-25


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This new Springer volume, which comes complete with a free DVD, is a comprehensive and detailed overview of the synapse with emphasis on the glutamatergic synapse. Most chapters relate the synapse’s functional aspects to its molecular mechanisms. This approach shows which mechanisms are characterized on both the functional and structural level and can thus be considered firmly established. It’s an important text for neuroscientists and disease-oriented clinicians in neurology.