Exotoxin A
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Pseudomonas Aeruginosa the Opportunist
Pseudomonas aeruginosa the Opportunist provides an in depth analysis of clinically relevant pathogenetic mechanisms and selected disease states. The book presents the most current discussion of pathogenic mechanisms logically arranged from the microbiology of the Pseudomonadaceae and initial mucosal adherence, progessing to microcolony formation and release of a wide assortment of virulence factors, and closing with the contribution of host cells to the disease process. Cellular and molecular disease mechanisms are covered, including genetic regulation of virulence-associated bacterial products. Future research trends are highlighted as well. Pseudomonas aeruginosa the Opportunist is an excellent reference for bacteriologists, clinical investigators, and practicing clinicians representing a variety of specialties, including ophthalmology, pediatrics, and transplantation.
Bacterial Protein Toxins
Author: K. Aktories
language: en
Publisher: Springer Science & Business Media
Release Date: 2013-03-14
In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein toxins. This refers especially to structural aspects of protein toxins but also holds true for genetics, molecular biology and biochemical mechanisms underlying the action of toxins. This volume covers the very current and exciting aspects of up-to-date bacterial toxicology and comprehensively reviews the most important bacterial protein toxins such as the intracellular acting toxins which exhibit enzyme activity, as well as those toxins that interact with cell plasma membranes by damaging the membranes (pore formation) or stimulating cell receptors (superantigens). This is the most current reference work on these important bacterial protein toxins, which are presented from the point of view of different disciplines such as pharmacology, microbiology, cell biology and protein chemistry.
The Bacteria
The reviews in this volume deal with questions of the mechanisms of pathogenesis and with organisms that have only recently been extensively studied on the molecular level.**The introductory section presents an overview of pathogenesis, emphasizing common elements and genetic mechanisms of regulation and a review on the population genetics of bacterial pathogenesis. The second section deals with the regulation of synthesis of surface components and their role in the colonization of the host and/or of the host immune systems. The third section covers the invasion and intracellular growth of facultative and obligate intracellular parasites. The last section is devoted to studies of the role of bacterial toxic products in pathogenesis.