Europrotective Natural Products
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Neuroprotective Natural Products
Author: Goutam Brahmachari
language: en
Publisher: John Wiley & Sons
Release Date: 2017-03-01
Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an overview of the most recent research advances in the field of bioactive natural products and natural drug formulations to combat today's destructive diseases. To this extent, the authors discuss the most severe neurological disorders in our modern civilization, such as Alzheimer's, Parkinson's and Huntington's disease, as well as ischemic brain stroke and depression. The emerging diversity of active compounds is covered in detail, including flavonoids, cannabinoids and oleanolic acid, while experts in the field explain the chemistry, mode of action and clinical aspects of novel neuroprotective natural products. In each case, the benefits of treatments using natural products are addressed from the perspective of modern as well as traditional medicine. With its multidisciplinary viewpoint, this is the ideal companion for medicinal and natural products chemists as well as neuroscientists, biochemists, pharmacologists, neurobiologists, and phytotherapists.
Annual Reports in Medicinal Chemistry: Roadmaps
Annual Reports in Medicinal Chemistry: Roadmaps, Volume 62 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. This release provides a compendium of information on newly approved drugs and compounds entering late-stage clinical trials, making it a valuable resource for graduate students pursuing research in medicinal chemistry - Reviews on hot topics of interest in small molecule drug discovery heavily pursued by industrial research organizations - Provides preclinical information in the context of chemical structures - Includes section editors who are highly knowledgeable and who can evaluate invited reviews for scientific rigor
Neurodegenerative Diseases
This reference book provides a comprehensive overview of models and therapeutic approaches against neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. It explores models based on the chemical, induced, cellular, genetic, transgenic, and 3D organoid approaches in neurodegenerative diseases. The book also reviews advantages and limitations of these models in designing the treatment strategies. Additionally, the book covers the emerging field of bioinformatics and its application in modeling various neurodegenerative diseases. Towards the end, the book highlights the role of holistic management, precision medicine, OMICS, and gene therapy against neurodegenerative disorders. It examines the implications and significance of stem cells therapy in translational models of neurodegenerative diseases. This book is an invaluable resource for researchers, neuroscientists, and neurosurgeons for getting in-depth information on the neurodegenerative models and therapeutic approaches. Key Features: Provides a comprehensive overview of neurodegenerative diseases and their models Examines the limitations associated with modeling neurodegenerative diseases Presents novel treatment strategies for Alzheimer's disease using cellular models Reviews importance of 3D organoid models for therapeutic approaches in Parkinson's disease Covers modeling techniques in understanding prion diseases Explores the role of genetic models in understanding Huntington's disease