Dynamical System Models In The Life Sciences And Their Underlying Scientific Issues
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Dynamical System Models In The Life Sciences And Their Underlying Scientific Issues
Author: Frederic Y M Wan
language: en
Publisher: World Scientific Publishing Company
Release Date: 2017-08-16
Broadly speaking, there are two general approaches to teaching mathematical modeling: 1) the case study approach, and 2) the method based approach (that teaches mathematical techniques with applications to relevant mathematical models). This text emphasizes instead the scientific issues for modeling different phenomena. For the natural or harvested growth of a fish population, we may be interested in the evolution of the population, whether it reaches a steady state (equilibrium or cycle), stable or unstable with respect to a small perturbation from equilibrium, or whether a small change in the environment would cause a catastrophic change, etc. Each scientific issue requires an appropriate model and a different set of mathematical tools to extract information from the model. Models examined are chosen to help explain or justify empirical observations such as cocktail drug treatments are more effective and regenerations after injuries or illness are fast-tracked (compared to original developments).Volume I of this three-volume set limits its scope to phenomena and scientific issues that are modeled by ordinary differential equations (ODE). Scientific issues such as signal and wave propagation, diffusion, and shock formation involving spatial dynamics to be modeled by partial differential equations (PDE) will be treated in Vol. II. Scientific issues involving randomness and uncertainty are examined in Vol. III.
Stability of Dynamical Systems
In the analysis and synthesis of contemporary systems, engineers and scientists are frequently confronted with increasingly complex models that may simultaneously include components whose states evolve along continuous time and discrete instants; components whose descriptions may exhibit nonlinearities, time lags, transportation delays, hysteresis effects, and uncertainties in parameters; and components that cannot be described by various classical equations, as in the case of discrete-event systems, logic commands, and Petri nets. The qualitative analysis of such systems requires results for finite-dimensional and infinite-dimensional systems; continuous-time and discrete-time systems; continuous continuous-time and discontinuous continuous-time systems; and hybrid systems involving a mixture of continuous and discrete dynamics. Filling a gap in the literature, this textbook presents the first comprehensive stability analysis of all the major types of system models described above. Throughout the book, the applicability of the developed theory is demonstrated by means of many specific examples and applications to important classes of systems, including digital control systems, nonlinear regulator systems, pulse-width-modulated feedback control systems, artificial neural networks (with and without time delays), digital signal processing, a class of discrete-event systems (with applications to manufacturing and computer load balancing problems) and a multicore nuclear reactor model. The book covers the following four general topics: * Representation and modeling of dynamical systems of the types described above * Presentation of Lyapunov and Lagrange stability theory for dynamical systems defined on general metric spaces * Specialization of this stability theory to finite-dimensional dynamical systems * Specialization of this stability theory to infinite-dimensional dynamical systems Replete with exercises and requiring basic knowledge of linear algebra, analysis, and differential equations, the work may be used as a textbook for graduate courses in stability theory of dynamical systems. The book may also serve as a self-study reference for graduate students, researchers, and practitioners in applied mathematics, engineering, computer science, physics, chemistry, biology, and economics.
Nonautonomous Dynamical Systems in the Life Sciences
Nonautonomous dynamics describes the qualitative behavior of evolutionary differential and difference equations, whose right-hand side is explicitly time dependent. Over recent years, the theory of such systems has developed into a highly active field related to, yet recognizably distinct from that of classical autonomous dynamical systems. This development was motivated by problems of applied mathematics, in particular in the life sciences where genuinely nonautonomous systems abound. The purpose of this monograph is to indicate through selected, representative examples how often nonautonomous systems occur in the life sciences and to outline the new concepts and tools from the theory of nonautonomous dynamical systems that are now available for their investigation.