Difficult To Treat Asthma
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Severe Asthma
Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma - epidemiology, diagnosis, mechanisms, treatment and management - but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various 'omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
Difficult To Treat Asthma
This book provides a practical, stepwise, evidence-based approach to effective management of patients with difficult to treat asthma. The impact of asthma on morbidity and healthcare utilization increases exponentially with severity. Severe refractory asthma accounts for less than 5% of all asthma. Its prevalence, however, is often overestimated as there are several other confounding factors that make asthma ‘difficult to treat’. Many novel (albeit expensive) therapies are now available and providers caring for patients with severe asthma are charged with selecting the best evidence treatment. This calls for complex and nuanced decision-making. Whether people with asthma gain and maintain control over their condition depends not only on the availability of effective drugs, but also multiple patient and healthcare provider behaviors. Therefore, now more than ever, it has become increasingly important to differentiate “difficult” from “severe refractory” asthma to allow identification of patients most likely to benefit from these therapies. This volume delves into the current understanding of mechanisms and increasingly recognized heterogeneity of this complex disease. It discusses a structured approach to identification and optimization of factors contributing to poor asthma control, including nonadherence, comorbidities and occupational/environmental triggers. The book includes ‘state of the art’ reviews on recent advances in traditional and targeted asthma therapies, as well as a glimpse into what the future may hold. Highlights include a comprehensive guide to management of severe asthma in children and pregnancy, as well as practical considerations to management of asthma based on different clinical phenotypes. Each chapter is authored by leading experts in the field who share their own clinical approach. This is an ideal guide for clinical pulmonologists and allergist/immunologists, as well as primary care providers, physician extenders in specialty practice, physicians in pulmonary/allergy training, and even industry partners.
Asthma, Health and Society
Author: Andrew Harver
language: en
Publisher: Springer Science & Business Media
Release Date: 2010-03-10
Asthma, Health, and Society A Public Health Perspective Edited by Andrew Harver, University of North Carolina at Charlotte, Charlotte Harry Kotses, Ohio University, Athens Asthma, Health, and Society is a comprehensive, current resource on this complex disease—its scope, human costs, and management—from a combined social ecology/public health perspective. This important and unique book proposes a concerted, multifaceted response and sets out the foundation for shaping this response, comprising individual and large-scale assessment, education, advocacy, and multiple forms of intervention. In clear, authoritative detail enhanced by figures, graphs, and references, contributors explain where universal standards need to be set, alliances need to be built (such as among agencies and institutions in a community), and what is currently known about: Pathophysiology, epidemiology, and social impact of asthma. Genetic and environmental factors; protective factors and risk markers. Effects in women, minorities, children, teens, and elders. Medical management, self-management, and home monitoring. Evidence-based interventions at the family, school, and community levels. Screening guidelines, compliance issues, and more. In the absence of a cure or clear-cut causes, Asthma, Health, and Society offers the most robust compilation of practical knowledge on its subject to benefit the range of public health and asthma professionals, researchers, teachers, and students