Determinants Of Neuronal Identity

Determinants of Neuronal Identity

Determinants of Neuronal Identity brings together studies of a wide range of vertebrate and invertebrate organisms that highlight the determinants of neuronal identity. Emphasis of this book is on how neurons are generated; how their developmental identities are specified; and to what degree those identities can be subsequently modified to meet the changing needs of the organism. This book also considers various techniques used in the analysis of different organisms. This volume is comprised of 15 chapters; the first of which introduces the reader to the specification of neuronal identity in Caenorhabditis elegans. The discussion then turns to neurogenesis and segmental homology in the leech, as well as intrinsic and extrinsic factors influencing the development of Retzius neurons in the leech nervous system. Drosophila is discussed next, with particular reference to neuronal diversity in the embryonic central nervous system, cell choice and patterning in the retina, and development of the peripheral nervous system. Other chapters explore endocrine influences on the postembryonic fates of neurons during insect metamorphosis; neuron determination in the nervous system of Hydra and in the mammalian cerebral cortex; and segregation of cell lineage in the vertebrate neural crest. This book will help scientists and active researchers in synthesizing a conceptual framework for further studies of neuronal specification.

Developmental Neurobiology

Developmental Neuroscience is one of the six core disciplines in Neuroscience, and yet no single volume, non-textbook reference exists on the market that provides researchers with more in-depth, high-level information on developmental neurobiology. Currently, anyone interested in the field at a higher level must sift through review articles published frequently and the more specific handbooks that focus on aspects of development rather than the field as a whole. This reference is the first of its kind to fill this need. It pulls together the relevant articles on the topic from the 10-volume Encyclopedia of Neuroscience (Academic Press, 2008) and serves as an affordable and immediate resource for scientists, postdocs, graduate students with an interest beyond the basic textbook materials on the subject. - The first and only comprehensive, single-volume reference for developmental neuroscience that goes beyond the basic textbook information - The 93 chapters cover topics ranging from cell fate determination, path finding, synapse generation, neural stem cells, to neurodegeneration and regeneration, carefully selected from the Encyclopedia of Neuroscience by one of the great developmental neuroscientists, Greg Lemke - The best researchers in the field provide their conclusions in the context of the latest experimental results

Comprehensive Developmental Neuroscience: Patterning and Cell Type Specification in the Developing CNS and PNS