Data Verification

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Data Science

This two volume set (CCIS 901 and 902) constitutes the refereed proceedings of the 4th International Conference of Pioneering Computer Scientists, Engineers and Educators, ICPCSEE 2018 (originally ICYCSEE) held in Zhengzhou, China, in September 2018. The 125 revised full papers presented in these two volumes were carefully reviewed and selected from 1057 submissions. The papers cover a wide range of topics related to basic theory and techniques for data science including mathematical issues in data science, computational theory for data science, big data management and applications, data quality and data preparation, evaluation and measurement in data science, data visualization, big data mining and knowledge management, infrastructure for data science, machine learning for data science, data security and privacy, applications of data science, case study of data science, multimedia data management and analysis, data-driven scientific research, data-driven bioinformatics, data-driven healthcare, data-driven management, data-driven eGovernment, data-driven smart city/planet, data marketing and economics, social media and recommendation systems, data-driven security, data-driven business model innovation, social and/or organizational impacts of data science.
Conducting GCP-Compliant Clinical Research

Conducting GCP-Compliant Clinical Research Wendy Bohaychuk and Graham Ball Good Clinical Research Practices, UK and Canada The overall aim of this work is to provide a reference book which describes the general framework for conducting GCP-compliant clinical research, particularly pharmaceutical industry clinical research. Wendy Bohaychuk and Graham Ball run a consultancy, GCRP Ltd., which has conducted over 820 GCP audits involving more than 200 companies in the last 10 years. More than 5,000 individuals have been involved in their training courses to help people perform GCP-compliant clinical research. They have authored several books and articles including: Standard operating procedures for investigators Standard operating procedures for sponsors and CROs GCP - an indexed reference Drawing on their wealth of experience, they have produced this enlightening and practical reference work which fills an educational gap in the understanding of GCP at all levels. Written in concise language simple enough to be accessible to those new in the field, the dozens of real-life stories and detailed case studies at the end of each chapter make the book an invaluable resource for the more experienced, highlighting what can go wrong in a clinical study: A study of prostate cancer in the UK - An investigator brochure was not provided. The company argued that a brochure was unnecessary because the drug was already marketed. Indeed it was - for hypertension! A study of cardiovascular surgery in the UK - The consent dates were changed (by overwriting) to indicate that the patients had provided consent before the study started. The original dates post-dated the start of the study. A study of hypertension in Germany - The investigator brochure predated the study by nine years! Checklists are provided throughout the book to help monitors, auditors and investigators ensure that nothing important is overlooked. The authors present the topic of GCP with remarkable clarity, insight and enthusiasm emphasizing that this code of practice was not designed to make studies more difficult for investigators or more expensive for sponsors and CROs but, in the final analysis, to ensure the safety and well-being of study participants and future patients who will benefit from well-conducted, GCP-compliant studies.
Correct Hardware Design and Verification Methods

This book constitutes the refereed proceedings of the 13th IFIP WG 10.5 Advanced Research Working Conference on Correct Hardware Design and Verification Methods, CHARME 2005, held in Saarbrücken, Germany, in October 2005. The 21 revised full papers and 18 short papers presented together with 2 invited talks and one tutorial were carefully reviewed and selected from 79 submissions. The papers are organized in topical sections on functional approaches to design description, game solving approaches, abstraction, algorithms and techniques for speeding (DD-based) verification, real time and LTL model checking, evaluation of SAT-based tools, model reduction, and verification of memory hierarchy mechanisms.