Data Analysis And Multiple Imputation For Two Level Nested Designs
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Data Analysis and Multiple Imputation for Two-level Nested Designs
This work examined methods to account for the clustering that occurs in nested clinical trial designs, which if ignored when analyzing or imputing data can result in invalid inference and misleading conclusions. We explored two distinct areas of research depending on whether the design is partially nested or fully nested.
Handbook of Advanced Multilevel Analysis
This new handbook is the definitive resource on advanced topics related to multilevel analysis. The editors assembled the top minds in the field to address the latest applications of multilevel modeling as well as the specific difficulties and methodological problems that are becoming more common as more complicated models are developed. Each chapter features examples that use actual datasets. These datasets, as well as the code to run the models, are available on the book’s website http://www.hlm-online.com . Each chapter includes an introduction that sets the stage for the material to come and a conclusion. Divided into five sections, the first provides a broad introduction to the field that serves as a framework for understanding the latter chapters. Part 2 focuses on multilevel latent variable modeling including item response theory and mixture modeling. Section 3 addresses models used for longitudinal data including growth curve and structural equation modeling. Special estimation problems are examined in section 4 including the difficulties involved in estimating survival analysis, Bayesian estimation, bootstrapping, multiple imputation, and complicated models, including generalized linear models, optimal design in multilevel models, and more. The book’s concluding section focuses on statistical design issues encountered when doing multilevel modeling including nested designs, analyzing cross-classified models, and dyadic data analysis. Intended for methodologists, statisticians, and researchers in a variety of fields including psychology, education, and the social and health sciences, this handbook also serves as an excellent text for graduate and PhD level courses in multilevel modeling. A basic knowledge of multilevel modeling is assumed.
Multiple Imputation of Missing Data in Practice
Multiple Imputation of Missing Data in Practice: Basic Theory and Analysis Strategies provides a comprehensive introduction to the multiple imputation approach to missing data problems that are often encountered in data analysis. Over the past 40 years or so, multiple imputation has gone through rapid development in both theories and applications. It is nowadays the most versatile, popular, and effective missing-data strategy that is used by researchers and practitioners across different fields. There is a strong need to better understand and learn about multiple imputation in the research and practical community. Accessible to a broad audience, this book explains statistical concepts of missing data problems and the associated terminology. It focuses on how to address missing data problems using multiple imputation. It describes the basic theory behind multiple imputation and many commonly-used models and methods. These ideas are illustrated by examples from a wide variety of missing data problems. Real data from studies with different designs and features (e.g., cross-sectional data, longitudinal data, complex surveys, survival data, studies subject to measurement error, etc.) are used to demonstrate the methods. In order for readers not only to know how to use the methods, but understand why multiple imputation works and how to choose appropriate methods, simulation studies are used to assess the performance of the multiple imputation methods. Example datasets and sample programming code are either included in the book or available at a github site (https://github.com/he-zhang-hsu/multiple_imputation_book). Key Features Provides an overview of statistical concepts that are useful for better understanding missing data problems and multiple imputation analysis Provides a detailed discussion on multiple imputation models and methods targeted to different types of missing data problems (e.g., univariate and multivariate missing data problems, missing data in survival analysis, longitudinal data, complex surveys, etc.) Explores measurement error problems with multiple imputation Discusses analysis strategies for multiple imputation diagnostics Discusses data production issues when the goal of multiple imputation is to release datasets for public use, as done by organizations that process and manage large-scale surveys with nonresponse problems For some examples, illustrative datasets and sample programming code from popular statistical packages (e.g., SAS, R, WinBUGS) are included in the book. For others, they are available at a github site (https://github.com/he-zhang-hsu/multiple_imputation_book)