Current Advances In Drug Delivery Through Fast Dissolving Disintegrating Dosage Forms

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Current Advances in Drug Delivery Through Fast Dissolving/Disintegrating Dosage Forms

Author: Vikas Anand Saharan
language: en
Publisher: Bentham Science Publishers
Release Date: 2017-05-11
Fast Dissolving/Disintegrating Dosage Forms (FDDFs) have been commercially available since the late 1990s. FDDFs were initially available as orodispersible tablets, and later, as orodipsersible films for treating specific populations (pediatrics, geriatrics, and psychiatric patients). Granules, pellets and mini tablets are among latest additions to these dosage forms, which are still in the development pipeline. As drug delivery systems, FDDFs enable quicker onset of action, immediate drug delivery, and sometimes offer bioavailability benefits due to buccal/sublingual absorption. With time, FDDF have evolved to deliver drugs in a sustained and controlled manner. Their current market and application is increasing in demands with advances in age adapted dosage forms for different patients and changing regulatory requirements that warrant mandatory assessments of new drugs and drug products before commercial availability. This book presents detailed information about FDDFs from their inception to recent developments. Readers will learn about the technical details of various FDDF manufacturing methods, formulation aspects, evaluation and methods to conduct clinical studies. The authors also give examples of marketed fast disintegrating/dissolving drug products in US, Europe, Japan, and India. This reference is ideal for pharmacology students at all levels seeking information about this specific form of drug delivery and formulation.
Formulating Pharma-, Nutra-, and Cosmeceutical Products from Herbal Substances

A practical and up-to-date discussion of the formulation and design of dosage forms and delivery systems containing herbal ingredients In Formulating Pharma-, Nutra-, and Cosmeceutical Products from Herbal Substances: Dosage Forms and Delivery Systems, a team of distinguished researchers delivers a step-by-step approach to preparing and manufacturing dosage forms and delivery systems. Intuitively organized with comprehensive coverage of the fundamentals, functional materials, manufacturing, and marketing of pharmaceutical, nutraceutical, and cosmeceutical products, the book also examines regulatory issues of quality, safety, and efficacy. The authors discuss essential formulation development and delivery information for novel and controlled delivery systems of herbal ingredients. Readers will also find: A thorough introduction to the basic principles of developing modern pharma-, nutra-, and cosmeceutical products from herbal substances Comprehensive explorations of conventional formulations, including issues of stability Practical discussions of advanced formulations, including chronotherapeutic delivery systems, liposome-based delivery of phytoconstituents, and nanoparticle mediated delivery of herbal actives Complete treatments of regulatory challenges, including nonclinical characterization and documentation for marketing authorizations of herbal formulations Perfect for professionals working in the herbal drug, natural product, and dietary supplement industries, Formulating Pharma-, Nutra-, and Cosmeceutical Products from Herbal Substances will also benefit academic researchers and graduate students studying herbal research, cosmetics, and pharmaceutical sciences.
Drug Delivery to the Oral Cavity

With contributions from recognized authorities in industry, academia, and government, this reference presents the state-of-the-art in the testing, formulation, and clinical evaluation of intraoral drug delivery products-summarizing intraoral dosage forms in various stages of research, as well as products currently on the market.