Cassandra In Reverse Reddit
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Target Discovery and Validation
Author: Alleyn T. Plowright
language: en
Publisher: John Wiley & Sons
Release Date: 2020-02-18
The modern drug developers? guide for making informed choices among the diverse target identification methods Target Discovery and Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and validation. With contributions from noted industry and academic experts, the book addresses the most recent chemical, biological, and computational methods. Additionally, the book highlights techologies that are applicable to ?difficult? targets and drugs directed at multiple targets, including chemoproteomics, activity-based protein profiling, pathway mapping, genome-wide association studies, and array-based profiling. Throughout, the authors highlight a range of diverse approaches, and target validation studies reveal how these methods can support academic and drug discovery scientists in their target discovery and validation research. This resource: -Offers a guide to identifying and validating targets, a key enabling technology without which no new drug development is possible -Presents the information needed for choosing the appropriate assay method from the ever-growing range of available options -Provides practical examples from recent drug development projects, e. g. in kinase inhibitor profiling Written for medicinal chemists, pharmaceutical professionals, biochemists, biotechnology professionals, and pharmaceutical chemists, Target Discovery and Validation explores the current methods for the identification and validation of drug targets in one comrpehensive volume. It also includes numerous practical examples.
A Field Guide to the North American Family
The very first work of fiction by the best-selling, acclaimed author of City on Fire--his piercingly beautiful treasure box of a novella about two families in the suburbs, now in a newly designed full-color edition For years, the Hungates and the Harrisons have coexisted peacefully in the same Long Island neighborhood, enjoying the pleasures and weathering the pitfalls of their suburban habitat. But when the patriarch of one family dies unexpectedly, the survivors face a stark imperative: adapt or face extinction. In sixty-three interlinked vignettes and striking accompanying photographs, the novella cuts multiple paths--which can be reconstructed in any order--through the lives of its richly imagined characters. Part art object, part Choose Your Own Adventure, A Field Guide to the North American Family is an innovative and deeply personal look at the ties that bind, as well as a poignant meditation on connection in a fragmented world.
Happy Girl Lucky (The Valentines, Book 1)
Introducing The Valentines – Happy Girl Lucky, the first book in the hilarious new romantic-comedy series by Holly Smale, author of the bestselling and critically acclaimed Geek Girl books.