Bloodpool

Gated Equilibrium Bloodpool Scintigraphy

Cardiac Amyloidosis

Cardiac amyloidosis (CA) is caused by the accumulation of amyloid fibrils in the extracellular space of the myocardium, with clinical manifestations including conduction disturbances and heart failure. CA has traditionally been considered a rare disease, lacking effective therapies and with a poor prognosis, but in recent years, increased possibilities for non-invasive diagnosis and greater awareness of the disease have led to the identification of a growing number of cases, challenging the concept of CA as a rare disease. This is why the ability to recognise and manage patients with CA should become part of the core curriculum of cardiologists, but also of internal medicine specialists, general practitioners, neurologists, nephrologists and haematologists. This book, written by leading experts in the field, will provide the state-of-the-art in the diagnosis and management of CA and will also discuss the latest research developments and future research directions. Thevolume appears to be a timely one, given the great interest of clinicians and researchers in CA and the exponential increase in publications in recent year, and will be of interest to cardiologists, internal medicine and other disciplines specialists who may encounter patients with CA in their clinical practice, as well as general practitioners.

Clinical Blood Pool MR Imaging

Magnetic resonance angiography has made great strides, with continuing improvements in hardware, pulse sequencing, and know-how allowing ever-increasing speed, resolution, and suppression of artifacts. However, an inherent physical barrier has always been limited SNR. Gadolinium contrast agents help to increase SNR by facilitating T1 relaxation, but they can be injected only at a finite rate and at a limited molar dose, and there is a rapid drop in c- centration following the brief arterial phase due to redistribution into the extracellular fluid compartment. With its sixfold increase in T1 relaxivity, blood pool distribution, and longer serum half-life, Vasovist® represents a new breakthrough which promises to revolutionize MRA image quality once again. This excellent treatise on Vasovist®, created by a team of exceptional faculty who are pioneers in MR angiography, covers the basic techniques, safety, efficacy, image processing, and pharmacoeconomic details, to successfully implement a new level of MRA image quality with this new contrast agent. In addition to improving all the usual arterial phase MRA - plications, the blood pool distribution opens up new possibilities, including detecting internal bleeding and imaging stent graft endoleaks, which are reviewed in detail. In the complex, competitive field of cardiovascular imaging, this book articulates the cutting edge in imaging vascular disease.