Biotransformations In Organic Chemistry
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Biotransformations in Organic Chemistry — A Textbook
Author: Kurt Faber
language: en
Publisher: Springer Science & Business Media
Release Date: 2012-12-06
The use of natural catalysts - enzymes - for the transformation of non-natural man-made organic compounds is not at all new: they have been used for more than one hundred years, employed either as whole cells, cell organelles or isolated enzymes [1]. Certainly, the object of most of the early research was totally different from that of the present day. Thus the elucidation of biochemical pathways and enzyme mechanisms was the main reason for research some decades ago. It was mainly during the 1980s that the enormous potential of applying natural catalysts to transform non-natural organic compounds was recognized. What started as a trend in the late 1970s could almost be called a fashion in synthetic organic chemistry in the 1990s. Although the early euphoria during the 'gold rush' in this field seems to have eased somewhat, there is still no limit to be seen for the future development of such methods. As a result of this extensive, recent research, there have been all estimated 8000 papers published on the subject [2-14]. To collate these data as a kind of 'super-review' would clearly be an impossible task and, furthermore, such a hypothetical book would be unpalatable for the non-expert.
Biotransformations in Organic Chemistry
Author: Kurt Faber
language: en
Publisher: Springer Science & Business Media
Release Date: 2000
The use of biocatalysts offers a remarkable arsenal of highly selective transformations for modern preparative organic chemistry. This book provides a basis for biocatalysts and a condensed introduction to the field. After a basic introduction into the use of biocatalysts, the principles of stereoselective transformations, kinetics, and enzyme handling are discussed, and the different types of reactions are explained according to the "reaction principle". This fourth edition includes new chapters on peroxidase reactions and on the handling of biocatalysts.
Biotransformations in Organic Chemistry
Author: Kurt Faber
language: en
Publisher: Springer Science & Business Media
Release Date: 2012-12-06
The use of natural catalysts -enzymes -for the transformation of non-natural man-made organic compounds is not at all new: they have been used for more than one hundred years, employed either as whole cells, cell organelles or isolated enzymes [1, 2]. Certainly, the object of most of the early research was totally different from that of the present day. Thus the elucidation of biochemical pathways and enzyme mechanisms was the main reason for research some decades ago. It was mainly during the 1980s that the enormous potential of applying natural catalysts to transform non-natural organic compounds was recognized. What started as a trend in the late 1970s could almost be called a fashion in synthetic organic chemistry in the 1990s. Although the early euphoria during the 'gold rush' in this field seems to have eased somewhat, there is still no limit to be seen for the future development of such methods. As a result of this extensive, recent research, there have been an estimated 12000 papers published on the subject. To collate these data as a kind of 'super-review' would clearly be an impossible task and, furthermore, such a hypothetical book would be unpalatable for the non-expert [3-6].