Biodegradable Iron Implants Development Processing And Applications
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Biodegradable Iron Implants: Development, Processing, and Applications
Author: VP Muhammad Rabeeh
language: en
Publisher: Springer Nature
Release Date: 2025-01-30
This book offers a comprehensive guide to iron-based biodegradable metals (BMs) for temporary implant applications, addressing the need for medical implants that can safely degrade within the human body, thereby eliminating the necessity for additional surgeries and reducing long-term complications. Beginning with an introductory overview of BMs, it explains their significance in modern medicine and outlines the essential requirements for these materials and a comparative analysis of magnesium, zinc, and iron-based alloys. This chapter lays the foundation for understanding BMs' role in advancing healthcare solutions. The second chapter focuses on the interaction between iron and the human body, detailing iron's degradation and mechanical characteristics in the physiological environment. It explains the potential degradation routes of iron both in vitro and in vivo, while discussing the advantages and limitations of iron as a BM for temporary implants, supported by references to relevant literature. The third Chapter looks at recent advancements in manufacturing techniques aimed at improving the effectiveness and safety of iron-based implants. It emphasizes material fabrication and explores various manufacturing routes, including powder metallurgy, casting, and additive manufacturing. The performance of components made through different methods in the physiological environment is also examined. In Chapter four, the book covers various metallurgical and surface modification techniques such as alloying, surface treatments, and composite fabrication. It highlights the importance of post-processing developed materials to enhance the properties of iron implants, ensuring controlled degradation and maintaining mechanical strength during the healing process. This chapter provides valuable insights into how to process and customize the characteristics of iron to meet specific medical needs, particularly in cardiovascular and orthopedic medicine. The fifth chapter explores the potential applications of iron-based BMs in various medical fields. It discusses possible uses in cardiovascular, orthopedic, and other medical applications, based on reported literature. The final chapter provide a Summary & Future Prospective of Fe based degradable implants. Overall, this book is targeted at individuals in the fields of biomedical engineering, materials science, and medical practice who are engaged in the development and utilization of medical implants. It aims to significantly advance ongoing efforts by shedding light on novel materials and manufacturing techniques in medical technology.
Degradation of Implant Materials
Author: Noam Eliaz
language: en
Publisher: Springer Science & Business Media
Release Date: 2012-08-21
This book reviews the current understanding of the mechanical, chemical and biological processes that are responsible for the degradation of a variety of implant materials. All 18 chapters will be written by internationally renowned experts to address both fundamental and practical aspects of research into the field. Different failure mechanisms such as corrosion, fatigue, and wear will be reviewed, together with experimental techniques for monitoring them, either in vitro or in vivo. Procedures for implant retrieval and analysis will be presented. A variety of biomaterials (stainless steels, titanium and its alloys, nitinol, magnesium alloys, polyethylene, biodegradable polymers, silicone gel, hydrogels, calcium phosphates) and medical devices (orthopedic and dental implants, stents, heart valves, breast implants) will be analyzed in detail. The book will serve as a broad reference source for graduate students and researchers studying biomedicine, corrosion, surface science, and electrochemistry.
Biodegradable Metals
Author: Hendra Hermawan
language: en
Publisher: Springer Science & Business Media
Release Date: 2012-07-15
This book in the emerging research field of biomaterials covers biodegradable metals for biomedical applications. The book contains two main parts where each of them consists of three chapters. The first part introduces the readers to the field of metallic biomaterials, exposes the state of the art of biodegradable metals, and reveals its application for cardiovascular implants. Some fundamental aspects to give basic understanding on metals for further review on the degradable ones is covered in chapter one. The second chapter introduces the concept of biodegradable metals, it's state of the art and discuses a shifted paradigm from inert to bioactive, from corrosion resistant to corrodible metals. The third chapter focuses on the challenges and opportunities of using biodegradable metals for cardiovascular applications. The second part exposes an example of biodegradable metals from its concept to applications where a complete study on metallic biodegradable stent is detailed from materials design, development, testing till the implant fabrication. The forth chapter reveals new alloys development devoted for metallic biodegradable stent based on required criteria derrived from clinical needs and current nondegradable stents properties. Degradation of the alloys in simulated arterial conditions and its effect to cells are exposed in chapter five. The both chapters are concluded with a benchmarking of some more recent researches on materials development and testing for biodegradable stents. Chapter six reveals the tranformation process of the materials into stent prototypes where a standard process for making 316L stainless steel stents was followed. The book is completed by a perspective on the use of biodegradable metals for biomedical applications in the era of tissue engineering.