Bacterial Genetics And Genomics
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Bacterial Genetics and Genomics
Our understanding of bacterial genetics has progressed as the genomics field has advanced. Genetics and genomics complement and influence each other; they are inseparable. Under the novel insights from genetics and genomics, once-believed borders in biology start to fade: biological knowledge of the bacterial world is being viewed under a new light and concepts are being redefined. Species are difficult to delimit and relationships within and between groups of bacteria – the whole concept of a tree of life – is hotly debated when dealing with bacteria. The DNA within bacterial cells contains a variety of features and signals that influence the diversity of the microbial world. This text assumes readers have some knowledge of genetics and microbiology but acknowledges that it can be varied. Therefore, the book includes all of the information that readers need to know in order to understand the more advanced material in the book.
Fundamental Bacterial Genetics
Fundamental Bacterial Genetics presents a conciseintroduction to microbial genetics. The text focuses on onebacterial species, Escherichia coli, but draws examples fromother microbial systems at appropriate points to support thefundamental concepts of molecular genetics. A solid balance ofconcepts, techniques and applications makes this book anaccessible, essential introduction to the theory and practice offundamental microbial genetics. FYI boxes - feature key experiments that lead to what we nowknow, biographies of key scientists, comparisons with other speciesand more. Study questions - at the end of each chapter, review and teststudents' knowledge of key chapter concepts. Key references - included both at chapter end and in a fullreference list at the end of the book. Full Chapter on Genomics, Bioinformatics and Proteomics -includes coverage of functional genomics and microarrays. Dedicated website – animations, study resources, webresearch questions and illustrations downloadable for powerpointfiles provide students and instructors with an enhanced,interactive experience.
Bacterial Genetics and Genomics
Understanding of bacterial genetics and genomics is fundamental to understanding bacteria and higher organisms, as well. Novel insights in the fields of genetics and genomics are challenging the once clear borders between the characteristics of bacteria and other life. Biological knowledge of the bacterial world is being viewed under a new light with input from genetic and genomics. Replication of bacterial circular and linear chromosomes, coupled (and uncoupled) transcription and translation, multiprotein systems that enhance survival, wide varieties of ways to control gene and protein expression, and a range of other features all influence the diversity of the microbial world. This text acknowledges that readers have varied knowledge of genetics and microbiology. Therefore, information is presented progressively, to enable all readers to understand the more advanced material in the book. This second edition of Bacterial Genetics and Genomics updates the information from the first edition with advances made over the past five years. This includes descriptions for 10 types of secretion systems, bacteria that can be seen with the naked eye, and differences between coupled transcription-translation and the uncoupled runaway transcription in bacteria. Topic updates include advances in bacteriophage therapy, biotechnology, and understanding bacterial evolution. Key Features Genetics, genomics, and bioinformatics integrated in one place Over 400 full-colour illustrations explain concepts and mechanisms throughout and are available to instructors for download A section dedicated to the application of genetics and genomics techniques, including a chapter devoted to laboratory techniques, which includes useful tips and recommendations for protocols, in addition to troubleshooting and alternative strategies Bulleted key points summarize each chapter Extensive self-study questions related to the chapter text and several discussion topics for study groups to explore further This book is extended and enhanced through a range of digital resources that include: Interactive online quizzes for each chapter Flashcards that allow the reader to test their understanding of key terms from the book Useful links for online resources associated with Chapters 16 and 17