Assembly Principles

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Principles of Bioinspired and Biomimetic Regenerative Medicine

Nature has developed a diverse of materials, structures, and processes that are highly optimized for various functions. Through the field of biomimicry and bioinspiration, engineers are enhancing their understanding of natural design principles and applying these insights to create complex engineering models across different scales. These innovative approaches are particularly appropriate to address challenges in tissue engineering and regenerative medicine. Natural materials and systems exhibit a diverse array of functions, including but not limited to structural support, signal transduction, charge transfer, self-assembly, self-organization, and self-replication. Consequently, nature’s "solution manual" is remarkably comprehensive. Despite significant advancements, the reconstruction of nature-inspired designs using synthetic materials presents ongoing challenges. As a result, nature and bioinspired materials and architectures have emerged as a paradigm shift within the realm of tissue engineering and regenerative medicine. This comprehensive guide aims to provide scientists with inspiration to address a variety of critical challenges in tissue regeneration by directly applying established design principles. A key focus of this volume is the utilization of bioinspired architectures in tissue engineering. It also emphasizes the development of nature-inspired structures through the integration of novel biological macromolecules, bioinspired polymers and hydrogels, as well as biomimetic ceramics. Furthermore, the text concentrates on the biochemical and biophysical dimensions of bioinspired surface engineering. Both dry-lab and wet-lab methodologies for characterizing nature and bio-inspired materials and structures are also addressed. The publication seeks to promote the development of high-level translational knowledge among both established and emerging scientists.
Contemporary Challenges to the Fundamental Principles of International Law and EU Interaction

Author: Gloria Fernández Arribas
language: en
Publisher: Springer Nature
Release Date: 2024-11-25
This book, finished in September 2023, addresses the fundamental principles enshrined in Resolution 2625 (XXV): sovereignty, the principle of non-intervention, the prohibition of the use of force, and self-determination. Studying these principles can help us understand some of the main features of international law and the international community in the 21st century: the role of traditional and new subjects alike; the sources of international law; issues of international responsibility; and new international challenges. For this purpose, the book analyses in each chapter the main controversial practices regarding principles. In addition, a section is devoted to an analysis of the particular relationship between the European Union and these principles, given the EU's unique role as an important evolution in international law as both a subject and treaty maker. Further, the EU provides an example of the institutionalisation of the international community and helps to solidify the concept. The book is chiefly intended for experts on International Law. Its purpose is to offer an updated vision of the international community through analysis of the core principles of international law, highlighting contradictions and problems regarding its application and interpretation. The book should also be of great interest and value to those starting careers in international law, offering them key insights into the international community and the roots of the international system.
Introduction to Human Factors and Ergonomics for Engineers

Emphasizing customer oriented design and operation, Introduction to Human Factors and Ergonomics for Engineers explores the behavioral, physical, and mathematical foundations of the discipline and how to apply them to improve the human, societal, and economic well being of systems and organizations. The book discusses product design, such as tools,