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Kidney & Pancreas Transplantation
Author: Ernesto Pompeo Molmenti
language: en
Publisher: Jaypee Brothers Medical Publishers Pvt. Limited
Release Date: 2014-12-10
Kidney & Pancreas Transplantation is a comprehensive collection of considerations for organ transplantation, starting from candidate evaluation to surgical techniques and complications, and cutting-edge material on robotic surgical techniques. Divided into 22 sections, comprising 72 chapters, the book clearly illustrates the step-by-step surgical procedures of kidney and pancreas transplantation surgeries. Topics include islet cell transplantation, epigenetics, imaging complications, pathology, dermatologic manifestations, obesity and metabolic syndromes. The section ‘Operative Techniques: Donor’ offers extensive coverage of live donor nephrectomy, methods for avoiding and managing hazards during live donor nephrectomies and deceased donor procurement. Kidney & Pancreas Transplantation has a multidisciplinary approach, comprised of contributions from internationally renowned nephrologists. It offers practical guidance and information relevant to a diverse audience of physicians. Key Points Contributions from multidisciplinary experts Edited by Professor Molmenti at the LIJ School of Medicine, New York 1230 (800 full colour) images, illustrations and tables
The Weak Hydrogen Bond
Author: Gautam R. Desiraju
language: en
Publisher: International Union of Crystal
Release Date: 2001
The weak or non-conventional hydrogen bond has been subject of intense scrutiny over recent years in several fields, in particular in structural chemistry, structural biology, and also in the pharmaceutical sciences. There is today a large body of experimental and theoretical evidence confirming that hydrogen bonds like C-H...O, N-H...pi, C-H...pi and even bonds like O-H...metal play distinctive roles in molecular recognition, guiding molecular association, and in determining molecular and supramolecular architectures. The relevant compound classes include organometallic complexes, organic and bio-organic systems, and also DNA and proteins. The book provides a comprehensive assessment of this interaction type, and is of interest to all those interested in structural and supramolecular science, including fields as crystal engineering and drug design.
From Hypertension to Heart Failure
Author: Michael Böhm
language: en
Publisher: Springer Science & Business Media
Release Date: 2012-12-06
Arterial hypertension, coronary heart disease and heart fail ure are the commonest cardiovascular conditions to present in clinical practice. Over the past few years it has become in creasingly clear that they are closely and causally interrelated and that their relationship can have a significant bearing on prognosis. Epidemiological studies have shown that arterial hypertension is one of the most important risk factors for de veloping heart failure. Only one in four patients with hyper tension is adequately managed, and in 50% of cases, the hypertension has not been recognised or treated. Patients with pre-existing hypertension who go on to suffer an acute myocardial infarction have usually not previously had typi cal angina symptoms, the infarct territory is larger, life threatening arrhythmias are commoner and hence in-hospi tal mortality and long-term prognosis are markedly worse. The presence of raised blood pressure in the post-infarct phase doubles the risk of manifest heart failure. The close relationship between hypertension, coronary heart disease and heart failure makes the choice of therapeu tic strategy particularly important. Agents and classes of agents that have prognostic value in all three conditions should be considered first, as synergy might result in addi tional benefits. In such patients, this sort of therapeutic deci sion-making might have further advantages. The use of these agents may prevent complications which are not yet clinically obvious (such as heart failure).