Ariella Yeo
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Mussolini's Italy
With Mussolini ’s Italy, R.J.B. Bosworth—the foremost scholar on the subject writing in English—vividly brings to life the period in which Italians participated in one of the twentieth century’s most notorious political experiments. Il Duce’s Fascists were the original totalitarians, espousing a cult of violence and obedience that inspired many other dictatorships, Hitler’s first among them. But as Bosworth reveals, many Italians resisted its ideology, finding ways, ingenious and varied, to keep Fascism from taking hold as deeply as it did in Germany. A sweeping chronicle of struggle in terrible times, this is the definitive account of Italy’s darkest hour.
Chemoresistance and Metastasis in Breast Cancer: Molecular Mechanisms and Novel Clinical Strategies
Breast cancer is one of the most prevalent malignancies and a major cause of cancer-associated death in women around the world. Chemotherapy, as the major systemic treatment for breast cancer, can help control or even eliminate metastatic lesions in breast cancer patients. However, the emergence of chemoresistance often leads to treatment failure and metastasis of breast cancer. Many studies have confirmed that breast cancer metastasis is closely related to chemoresistance, and both of these events are regulated by a variety of genetic, epigenetic, and environmental factors. In clinical practice, breast cancer with resistance to chemotherapy is significantly associated with a high potential of distant metastasis and poor prognosis. Chemoresistance and metastasization remain the leading causes of breast cancer-related death. This Research Topic aims to uncover the still unclear underlying molecular mechanisms for chemoresistance and metastasis, as well as report the latest progress related to new biomarkers, therapeutic targets and development of new treatment strategies which will contribute to improved therapeutic efficacy and prognosis for breast cancer patients. We welcome Original Research, Reviews, Perspective and Opinion articles, focusing on but not limited to: - High-throughput analysis to discover chemoresistance and metastasis related molecules - Investigating predictive biomarkers in clinical research - Evaluating the clinical application value of specific therapeutic targets - Development of novel treatment strategies, such as targeted therapy, immunotherapy*, and nanotherapy - The construction and application of in vivo/in vitro research models in investigating the molecular mechanisms or evaluating drug susceptibility - The association between non-coding RNAs and chemoresistance and metastasis of breast cancer - The role of cancer stem cells in chemoresistance and metastasis of breast cancer - The interaction between the tumor microenvironment and breast cancer cells in modulating chemoresistance and metastasis of breast cancer *We recommend that papers on immunotherapy are submitted to the Research Topic “Immunotherapy as an Evolving Approach for the Treatment of Breast Cancer” at https://www.frontiersin.org/research-topics/13346 if the submission date is before 30th August 2020 Studies demonstrating the applicability of anticancer modalities must present a minimum of two well-authenticated cancer cell lines.
The Routledge Companion to Asian Cinemas
Balancing leading scholars with emerging trendsetters, this Companion offers fresh perspectives on Asian cinemas and charts new constellations in the field with significance far beyond Asian cinema studies. Asian cinema studies – at the intersection of film/media studies and area studies – has rapidly transformed under the impact of globalization, compounded by the resurgence of a variety of nationalist discourses as well as counter-discourses, new socio-political movements, and the possibilities afforded by digital media. Differentiated experiences of climate change and the COVID-19 pandemic have further heightened interest in the digital everyday and the renewed geopolitical divide between East and West, and between North and South. Thematized into six sections, the 46 chapters in this anthology address established paradigms of scholarship and viewership in Asian cinemas like extreme genres, cinephilia, festivals, and national cinema, while also highlighting political and archival concerns that firmly situate Asian cinemas within local and translocal milieus. Underrepresented cinemas of North Korea, Bangladesh, Laos, Indonesia, Malaysia, Taiwan, Thailand, and Cambodia, appear here amidst a broader cross-regional, comparative approach. An ideal resource for film, media, cultural and Asian studies researchers, students, and scholars, as well as informed readers with an interest in Asian cinemas.