Ai Assisted Computational Approaches For Immunological Disorders
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AI-Assisted Computational Approaches for Immunological Disorders
Based on accelerated computing and advanced algorithms, artificial intelligence (AI) has become a game-changer in diverse fields. In biomedical science, AI models based on machine learning, deep learning, and generative AI, together with upgraded computational and systems biology, provide smart, precise, and personalized medicine and healthcare. In the field of clinical immunology, which deals with intrinsic complicated immune systems for combating immunological disorders, AI technologies have the potential to solve problems based on identification, prediction, simulation, and modeling. AI algorithms may impact sustainable clinical healthcare and future immunology diagnoses. AI-Assisted Computational Approaches for Immunological Disorders explores precision clinical medicine and personalized healthcare in major immunological disorders, such as immunodeficiency, autoimmune diseases, allergies, asthma, cancers, and neurological diseases. It analyzes clinical healthcare big data, genomics, and high-throughput multiple omics based on single-cell and high-dimensional data for their technical advances, clinical applications, challenges, and future directions. Covering topics such as cell therapy, reducing complications, and drug development, this book is an excellent resource for immunologists, biologists, healthcare practitioners, professionals, researchers, scholars, academicians, and more.
IMMUNOINFORMATICS IN THE AGE OF AI: MACHINE LEARNING METHODS FOR IMMUNE SYSTEM MODELING
Author: Dr. Calvin Ronchen Wei
language: en
Publisher: Xoffencer International Book Publication house
Release Date: 2024-11-28
Immunoinformatics, an interdisciplinary field at the nexus of immunology, bioinformatics, and computational science, has been profoundly transformed by the advent of artificial intelligence (AI) and machine learning (ML) technologies. As the immune system is an intricate and dynamic network responsible for protecting organisms from pathogens, its study presents vast complexities requiring sophisticated computational tools. The integration of ML has enabled significant strides in understanding immune responses, predicting immune epitopes, designing vaccines, and modeling interactions between pathogens and the host immune system. ML algorithms, particularly those utilizing deep learning frameworks, have shown remarkable capabilities in analyzing vast genomic, proteomic, and transcriptomic datasets, revealing patterns and insights that were previously beyond human reach. These advancements are particularly crucial in the current era, where rapid responses to emerging diseases and pandemics necessitate unprecedented speed and precision in immune system research. AI-powered tools have revolutionized vaccine development by predicting antigenic determinants with high accuracy, thereby reducing reliance on traditional trial-and-error methods. This approach has accelerated the development of mRNA vaccines, which played a critical role during the COVID-19 pandemic. Furthermore, ML techniques like support vector machines, neural networks, and ensemble learning have been employed to simulate immune system dynamics, enabling researchers to forecast immune responses to various interventions. These models are instrumental in identifying biomarkers for autoimmune diseases, allergies, and cancer immunotherapy, paving the way for personalized medicine. Moreover, the incorporation of natural language processing in immunoinformatics has facilitated the curation and synthesis of vast biomedical literature, providing researchers with actionable insights into immune-related mechanisms and therapies. However, the application of ML in immunoinformatics is not without challenges. Issues such as data heterogeneity, interpretability of ML models, and the need for high-quality annotated datasets remain significant barriers. Ethical considerations, including data privacy and the equitable distribution of AI-enabled solutions, are also critical concerns. Addressing these challenges requires collaborative efforts between immunologists, data scientists, and ethicists, ensuring that advancements in AI are harnessed responsibly and inclusively
Microbiome Therapeutics
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