Advanced Techniques In Biophysics
Download Advanced Techniques In Biophysics PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Advanced Techniques In Biophysics book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages.
Advanced Techniques in Biophysics
Author: José Luis R. Arrondo
language: en
Publisher: Springer Science & Business Media
Release Date: 2007-04-21
Technical advancements are basic elements in our life. In biophysical studies, new applications and improvements in well-established techniques are being implemented every day. This book deals with advancements produced not only from a technical point of view, but also from new approaches that are being taken in the study of biophysical samples, such as nanotechniques or single-cell measurements. This book constitutes a privileged observatory for reviewing novel applications of biophysical techniques that can help the reader enter an area where the technology is progressing quickly and where a comprehensive explanation is not always to be found.
Methods in Modern Biophysics
Author: Bengt Nölting
language: en
Publisher: Springer Science & Business Media
Release Date: 2013-03-09
Incorporating dramatic recent advances, this textbook presents a fresh and timely introduction to modern biophysical methods. An array of new, faster and structurally higher-resolving power biophysical methods now enables scientists to examine the examination of the mysteries of life at a molecular level. So students and researchers alike need to know the technological details behind the latest methods so they can choose appropriate tools and make optimal use of them. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, and proteomics. Containing much information previously unavailable in tutorial form, Methods in Modern Biophysics employs worked examples and more than 260 illustrations to fully detail the techniques and their underlying mechanisms. The book was written for advanced undergraduateand graduate students, postdocs, researchers, lecturers and professors in biophysics, biochemistry, general biology and related fields.
Applied Biophysics for Drug Discovery
Applied Biophysics for Drug Discovery is a guide to new techniques and approaches to identifying and characterizing small molecules in early drug discovery. Biophysical methods are reasserting their utility in drug discovery and through a combination of the rise of fragment-based drug discovery and an increased focus on more nuanced characterisation of small molecule binding, these methods are playing an increasing role in discovery campaigns. This text emphasizes practical considerations for selecting and deploying core biophysical method, including but not limited to ITC, SPR, and both ligand-detected and protein-detected NMR. Topics covered include: • Design considerations in biophysical-based lead screening • Thermodynamic characterization of protein-compound interactions • Characterizing targets and screening reagents with HDX-MS • Microscale thermophoresis methods (MST) • Screening with Weak Affinity Chromatography • Methods to assess compound residence time • 1D-NMR methods for hit identification • Protein-based NMR methods for SAR development • Industry case studies integrating multiple biophysical methods This text is ideal for academic investigators and industry scientists planning hit characterization campaigns or designing and optimizing screening strategies.