Advanced Materials And Techniques For Biosensors And Bioanalytical Applications
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Advanced Materials and Techniques for Biosensors and Bioanalytical Applications
Bioanalytical science and its technological subdomain, biosensors, are ever-evolving subjects, striving for rapid improvement in terms of performance and expanding the target range to meet the vast societal and market demands. The key performance factors for a biosensor that drive the research are selectivity, sensitivity, response time, accuracy, and reproducibility, with additional requirements of its portability and inexpensive nature. These performance factors are largely governed by the materials and techniques being used in these bioanalytical platforms. The selection of materials to meet these requirements is critical, as their interaction or involvement with the biological recognition elements should initiate or improve these performance factors. The technique discussed primarily applies to transducers involved in converting a biochemical signal to optical or electrical signals. Over the years, the emergence of novel materials and techniques has drastically improved the performance of these bioanalytical systems, enabling them to expand their analytical horizon. These advanced materials and techniques are central to modern bioanalytical and biosensor research. Advanced Materials and Techniques for Biosensors and Bioanalytical Applications provides a comprehensive review of the subject, including a knowledge platform for both academics and researchers. Considering biosensors as a central theme to this book, an outline on this subject with background principles has been included, with a scope of extending the utility of the book to coursework in graduate and postgraduate schools. Features: • Basic principles on different classes of biosensors, recent advances and applications • Smart materials for biosensors and other rapid, portable detection devices • Metal nanoparticles and nanocrystals for analytical applications • Carbon-based nanoparticles and quantum dots for sensing applications • Nanozymes as potential catalysts for sensing applications • Bioelectrochemiluminescence and photoelectrochemical-based biosensors • Paper electronics and paper-based biosensors • Microbial biosensors: artificial intelligence, genetic engineering, and synthetic biology • Biofuel cells as a signal transduction platform • FET-based biosensors, including ISFET and BioFET This book serves as a reference for scientific investigators and a textbook for a graduate-level course in biosensors and advanced bioanalytical techniques.
Field-effect Transistor Biosensors for Rapid Pathogen Detection
Author: Naif H M Al-Hardan
language: en
Publisher: Royal Society of Chemistry
Release Date: 2024-05-03
Looking to prevent future outbreaks of deadly pathogens by early detection? Infectious diseases continue to be a challenge that necessitates increased precision in detection and integration to achieve accurate diagnosis at the point of care (PoC). Field-effect transistors (FETs) have been investigated widely as biosensors for pathogen detection, with advantages such as label-free and real-time detection capabilities. These biosensors have: a high level of sensitivity, a remarkable capacity for miniaturization, a molecular minimum limit of detection (LoD), and seamless integration with semiconductor technology In this title, we have invited expert scientific researchers to share their experience in this field. This book focuses on the application and possibility of FETs as biosensors, for rapid and real time detection of pathogens that affect human life. The lack of commercially available efficient devices that can be deployed for this task resulted in the recent global spread of the SARS-CoV-19 virus. The book is an attempt to keep interested parties up to date. Aimed at scientists and engineers (researchers, academics, and postgraduate students) who are interested in developing and using BioFET based sensors, the information in this book is crucial to help prevent future outbreaks of pathogens which bring with them significant impacts on human health and wellbeing.
Medical Biosensors for Point of Care (POC) Applications
Medical Biosensors for Point of Care (POC) Applications discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care. Part 1 covers the fundamentals of medical biosensors for point-of-care applications. Chapters in part 2 go on to look at materials and fabrication of medical biosensors while the next part looks at different technologies and operational techniques. The final set of chapters provide an overview of the current applications of this technology. Traditionally medical diagnostics have been dependent on sophisticated technologies which only trained professionals were able to operate. Recent research has focused on creating point-of-care diagnostic tools. These biosensors are miniaturised, portable, and are designed to be used at the point-of-care by untrained individuals, providing real-time and remote health monitoring. - Provides essential knowledge for designers and manufacturers of biosensors for point-of-care applications - Provides comprehensive coverage of the fundamentals, materials, technologies, and applications of medical biosensors for point-of-care applications - Includes contributions from leading international researchers with extensive experience in developing medical biosensors - Discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care