Advanced Computational Methods For Oncological Image Analysis


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Advanced Computational Methods for Oncological Image Analysis


Advanced Computational Methods for Oncological Image Analysis

Author: Leonardo Rundo

language: en

Publisher: Mdpi AG

Release Date: 2021-12-06


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Cancer is the second most common cause of death worldwide and encompasses highly variable clinical and biological scenarios. Some of the current clinical challenges are (i) early diagnosis of the disease and (ii) precision medicine, which allows for treatments targeted to specific clinical cases. The ultimate goal is to optimize the clinical workflow by combining accurate diagnosis with the most suitable therapies. Toward this, large-scale machine learning research can define associations among clinical, imaging, and multi-omics studies, making it possible to provide reliable diagnostic and prognostic biomarkers for precision oncology. Such reliable computer-assisted methods (i.e., artificial intelligence) together with clinicians' unique knowledge can be used to properly handle typical issues in evaluation/quantification procedures (i.e., operator dependence and time-consuming tasks). These technical advances can significantly improve result repeatability in disease diagnosis and guide toward appropriate cancer care. Indeed, the need to apply machine learning and computational intelligence techniques has steadily increased to effectively perform image processing operations-such as segmentation, co-registration, classification, and dimensionality reduction-and multi-omics data integration.

Advanced Computational Methods for Knowledge Engineering


Advanced Computational Methods for Knowledge Engineering

Author: Hoai An Le Thi

language: en

Publisher: Springer Nature

Release Date: 2019-12-19


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This proceedings book contains 37 papers selected from the submissions to the 6th International Conference on Computer Science, Applied Mathematics and Applications (ICCSAMA 2019), which was held on 19–20 December, 2019, in Hanoi, Vietnam. The book covers theoretical and algorithmic as well as practical issues connected with several domains of Applied Mathematics and Computer Science, especially Optimization and Data Science. The content is divided into four major sections: Nonconvex Optimization, DC Programming & DCA, and Applications; Data Mining and Data Processing; Machine Learning Methods and Applications; and Knowledge Information and Engineering Systems. Researchers and practitioners in related areas will find a wealth of inspiring ideas and useful tools & techniques for their own work.

Computational Methods for Precision Oncology


Computational Methods for Precision Oncology

Author: Alessandro Laganà

language: en

Publisher: Springer Nature

Release Date: 2022-03-01


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Precision medicine holds great promise for the treatment of cancer and represents a unique opportunity for accelerated development and application of novel and repurposed therapeutic approaches. Current studies and clinical trials demonstrate the benefits of genomic profiling for patients whose cancer is driven by specific, targetable alterations. However, precision oncologists continue to be challenged by the widespread heterogeneity of cancer genomes and drug responses in designing personalized treatments. Chapters provide a comprehensive overview of the computational approaches, methods, and tools that enable precision oncology, as well as related biological concepts. Covered topics include genome sequencing, the architecture of a precision oncology workflow, and introduces cutting-edge research topics in the field of precision oncology. This book is intended for computational biologists, bioinformaticians, biostatisticians and computational pathologists working in precision oncology and related fields, including cancer genomics, systems biology, and immuno-oncology.