1984 What Rat
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Initiation and Promotion in Skin Or Liver Neoplasia
Initiation and Promotion in Skin or Liver Neoplasia is the only source of its kind that presents a comprehensive compilation of in vivo initiation/promotion studies that involve neoplastic changes in the skin or liver of experimental animals. The book surveys world literature over the past 65 years from almost 2,000 original studies covering nearly 200 journals in 9 languages. Publications reviewed consist of primary peer-reviewed papers, as well as those abstracts, meeting reports, and review articles, containing original data. Papers measuring both pre-neoplastic or neoplastic changes are included. The summaries for each study included in the book are highly formatted resumes that have four principal components which indicate: 1) What was done in the study; 2) How the study was done (e.g, methods); 3) The precise results obtained; 4) Individual critiques using GLP (Good Lab Practice) standards. Initiation and Promotion in Skin or Liver Neoplasia provides an indispensable abstracted reference resource for scientists, toxicologists, cancer researchers, litigators, regulators, environmentalists, policy analysts, and industry-based investigators.
Spinal Afferent Processing
Author: T.L. Yaskh
language: en
Publisher: Springer Science & Business Media
Release Date: 2013-06-29
Some 29 scientists from the fields of neuroanatomy, neurochemistry, neu rophysiology, neuropharmacology, and behavior have contributed their ef forts to this testimonial on behalf of the contributions made by Dr. F. W. L. Kerr to science and to those with whom he interacted. The intention of the contributors to this volume was to deal with the manifold advances that pertain to the substrates in spinal cord relating to the processing of sensory infor mation, a subject that in one form or another provoked time and again Kerr's native enthusiasm for research. The organization of the book follows a natural course from the peripheral innervation of the somatic and visceral organs (Winkelmann, Chapter 2) to the effective stimuli that activate these fibers and give rise to sensation under normal and pathological conditions (Campbell and Meyer, Chapter 3; Dubner and colleagues, Chapter 13; Dyck, Chapter 14) to the course these afferent systems take to enter the spinal cord (Coggeshall, Chapter 4) and to the organization of the systems through which this afferent information reaches the brain (Willis, Chapter 11; Vierck and colleagues, Chapter 12).
Peptide Receptors, Part I
During the last few years, the pace of research in the field of neuropeptide receptors has increased steadily: new neuropeptides were discovered, and the classification of receptor subtypes has been refined. It thus appeared essential to update the information. Peptide Receptors Part I summarizes current knowledge on ten distinct peptide families. This volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry, and immunocytochemistry images. Application of these classical techniques and of new approaches such as transgenic and knock-out animals has revealed a distinct species and tissue specific variation in receptor subtypes expression and pharmacology in the mammalian central nervous system. The functional role of neuropeptides and their receptors in the CNS has been investigated thanks to the development of potent and selective receptor antagonists and agonists. The development of specific neuropeptide-related molecules will help to get a better understanding of receptor subtype physiology and neuronal distribution and may lead to innovative treatments in a variety of brain disorders.