Hhh Therapy
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Handbook of Neuroemergency Clinical Trials
During the 1990's, scientific advances in understanding the mechanisms and pathophysiology of acute central nervous system injury were offset by a history of disappointing results from Phase III clinical trials of novel neuroprotective drugs. Numerous novel compounds were "tested, and seemingly fell by the wayside. This book is intended to focus on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. The authors explore the issues facing research in this area and the strategies that might lead to future success in this critical area of unmet medical need. It represents a compendium of information gained from over 20 years of clinical trial experience in areas of acute neurology and neurosurgery. From the knowledge of clinical assessment using standardized tools, to the intricate design of difficult hyper-acute neuroemergencies trials, the reader will benefit from the authors' perspectives.* Presents new perspectives on acute neuroemergency clinical trials * Includes insights from clinical pharmacology and industry perspectives* Discusses historical lessons learned from early and recent trials in acute neuroscience populations
Angioplasty, Various Techniques and Challenges in Treatment of Congenital and Acquired Vascular Stenoses
Author: Thomas Forbes
language: en
Publisher: BoD – Books on Demand
Release Date: 2012-03-14
The field of performing transcatheter interventions to treat vascular lesions has exploded over the past 20 years. Not only has the technology changed, especially in the arena of balloon/stent devices, but the techniques of approaching complex lesions has evolved over the past decade. Lesions that no one would have imagined treating back in the 1990's are now being done routinely in the catheterization suite. This book provides an update on the current techniques and devices used to treat a wide variety of lesions. Though, at first, the outward appearance of the topics appears to be varied, they are all related by the common thread of treating vascular lesions. We hope, by publishing this book, to accomplish two things: First, to offer insight from experts in their field to treat, both medically and procedurally, complex vascular lesions that we frequently encounter. Secondly, we hope to promote increased communication between areas of medicine that frequently don't communicate, between adult interventional cardiologists, pediatric interventional cardiologists, interventional radiologists, and neurosurgeons. Much can be learned from our respective colleagues in these areas which can further our own world of interventions.
A Practical Approach to Neuroanesthesia
Author: Glenn P. Gravlee
language: en
Publisher: Lippincott Williams & Wilkins
Release Date: 2013-06-10
A Practical Approach to Neuroanesthesia is the latest addition in the Practical Approach to Anesthesiology series. This important volume provides updated information on the approach and management for both adult and pediatrice patients' physiology dealing with neurosurgical conditions. The outline format with key concepts provides rapid access to clear diagnostic and management guidance for a broad range of neurosurgical and neuroanesthesiology procedures as well as neurocritical care problems. Each chapter provides a comprehensive review of clinical practice focusing on key points, clinical pearls, and key references. This new text provides expert recommendations on critical pre-operative, intra-operative and post-operative care for both adult and pediatric patients undergoing neurosurgical and neuroradiologic procedures. A Practical Approach to Neuroanesthesia is a concise, portable reference suitable for use by anesthesia residents and fellows, practicing anesthesiologists, nurse anesthetists, and anesthesiologist assistants.