Dependent Fluid Accumulation
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Capillary Fluid Exchange
Author: Joshua Scallan
language: en
Publisher: Morgan & Claypool Publishers
Release Date: 2010
The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular walls and the surface areas of permeable structures comprising the endothelial barrier to fluid and solute exchange, as well as within the extracellular matrix and lymphatics. In addition to its role in the regulation of vascular volume, transcapillary fluid filtration also allows for continuous turnover of water bathing tissue cells, providing the medium for diffusional flux of oxygen and nutrients required for cellular metabolism and removal of metabolic byproducts. Transendothelial volume flow has also been shown to influence vascular smooth muscle tone in arterioles, hydraulic conductivity in capillaries, and neutrophil transmigration across postcapillary venules, while the flow of this filtrate through the interstitial spaces functions to modify the activities of parenchymal, resident tissue, and metastasizing tumor cells. Likewise, the flow of lymph, which is driven by capillary filtration, is important for the transport of immune and tumor cells, antigen delivery to lymph nodes, and for return of filtered fluid and extravasated proteins to the blood. Given this background, the aims of this treatise are to summarize our current understanding of the factors involved in the regulation of transcapillary fluid movement, how fluid movements across the endothelial barrier and through the interstitium and lymphatic vessels influence cell function and behavior, and the pathophysiology of edema formation. Table of Contents: Fluid Movement Across the Endothelial Barrier / The Interstitium / The Lymphatic Vasculature / Pathophysiology of Edema Formation
Huether and McCance's Understanding Pathophysiology, Canadian Edition - E-Book
Author: Kelly Power-Kean
language: en
Publisher: Elsevier Health Sciences
Release Date: 2022-01-08
**Textbook and Academic Authors Association (TAA) Textbook Excellence Award Winner, 2024** Prepare for Canadian nursing practice with a solid understanding of pathophysiology and disease! Huether and McCance's Understanding Pathophysiology, 2nd Canadian Edition covers the basic concepts of pathophysiology and disease processes from a Canadian perspective. Clear descriptions and vibrant illustrations make it easier to understand body systems and the mechanisms of disease, and online resources bring pathophysiology concepts to life. Developed for Canadian nursing students by educators Kelly Power-Kean, Stephanie Zettel, and Mohamed Toufic El-Hussein, this text prepares students for success on the Next Generation NCLEX®, CPNRE®, and REx-PNTM and also in clinical practice. - Introduction to Pathophysiology provides an entrance to the science of pathophysiology and explains why it is important. - Lifespan coverage includes nine separate chapters on developmental alterations in pathophysiology and special sections with aging and pediatrics content. - Canadian drug and treatment guidelines familiarize you with aspects of clinical practice you will encounter. - Coverage of diseases includes their pathophysiology, clinical manifestations, and evaluation and treatment. - Canadian lab values provide the core fundamental information required for practice in Canada. - Canadian morbidity statistics provide you with the Canadian context in which you will be practising. - Algorithms and flowcharts of diseases and disorders make it easy to follow the sequential progression of disease processes. - Health Promotion boxes emphasize evidence-based care and align with the Canadian curriculum. - Risk Factors boxes highlight important safety considerations associated with specific diseases. - Quick Check boxes test your understanding of important chapter concepts. - End-of-chapter Did You Understand? summaries make it easy to review the chapter's major concepts. - Key Terms are set in blue, boldface type and listed at the end of each chapter - Glossary of approximately 1,000 terms is included on the Evolve website with definitions of important terminology.
CRC Handbook of Marine Mammal Medicine
CRC Handbook of Marine Mammal Medicine, Second Edition is the only handbook specifically devoted to marine mammal medicine and health. With 66 contributors working together to craft 45 scientifically-based chapters, the text has been completely revised and updated to contain all the latest developments in this field. Building upon the solid foundation of the previous edition, the contents of this book are light-years ahead of the topics presented in the first edition. See what's new in the Second Edition: Marine mammals as sentinels of ocean health Emerging and resurging diseases Thorough revision of the Immunology chapter Diagnostic imaging chapters to illustrate new techniques Quick reference for venipuncture sites in many marine mammals Unusual mortality events and mass strandings New topics such as a chapter on careers Wider scope of coverage including species outside of the United States and Canada Filled with captivating illustrations and photographs, the Handbook guides you through the natural history of cetaceans, pinnipeds, manatees, sea otters, and polar bears. Prepared in a convenient, easy-to-use format, it is designed specifically for use in the field. Covering more than 40 topics, this one-of-a-kind reference is packed with data. The comprehensive compilation of information includes medicine, surgery, pathology, physiology, husbandry, feeding and housing, with special attention to strandings and rehabilitation. The CRC Handbook of Marine Mammal Medicine, Second Edition is still a must for anyone interested in marine mammals.